| January 2022 |
| Date | Time | Opponent | Venue | Result |
| Sat. 8 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST22:00 ET22:00 23:00 BRT23:00 8:00 PM CT | Tijuana | Estadio Azteca | W 2-0 |
| Sat. 15 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST22:00 ET22:00 23:00 BRT23:00 8:00 PM CT | FC Juárez | Estadio Azteca | W 1-0 |
| Sat. 22 | 7:06 PM PT8:06 PM MT9:06 PM CT10:06 PM ET3:06 (+1) GMT4:06 3:06 3:06 AM 5:06 KSA14:06 AM AET8:36 (+1) IST10:36 PM VEN7:06 (+1) UAE11:06 AM SST11:06 10:06 8:06 PM MST9:06 PM CST10:06 PM EST22:06 ET22:06 23:06 BRT23:06 8:06 PM CT | Monterrey | Estadio BBVA | D 2-2 |
| February 2022 |
| Date | Time | Opponent | Venue | Result |
| Mon. 7 | 7:05 PM PT8:05 PM MT9:05 PM CT10:05 PM ET3:05 (+1) GMT4:05 3:05 3:05 AM 5:05 KSA14:05 AM AET8:35 (+1) IST10:35 PM VEN7:05 (+1) UAE11:05 AM SST11:05 10:05 8:05 PM MST9:05 PM CST10:05 PM EST22:05 ET22:05 23:05 BRT23:05 8:05 PM CT | León | Estadio Leon (Nou Camp) | W 1-0 |
| Sat. 12 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET1:00 (+1) GMT2:00 1:00 1:00 AM 3:00 KSA12:00 AM AET6:30 (+1) IST8:30 PM VEN5:00 (+1) UAE9:00 AM SST9:00 8:00 6:00 PM MST7:00 PM CST8:00 PM EST20:00 ET20:00 21:00 BRT21:00 6:00 PM CT | Necaxa | Estadio Azteca | L 1-2 |
| Sun. 20 | 4:05 PM PT5:05 PM MT6:05 PM CT7:05 PM ET0:05 (+1) GMT1:05 0:05 12:05 AM 2:05 KSA11:05 AM AET5:35 (+1) IST7:35 PM VEN4:05 (+1) UAE8:05 AM SST8:05 7:05 5:05 PM MST6:05 PM CST7:05 PM EST19:05 ET19:05 21:05 BRT20:05 5:05 PM CT | Toluca | Estadio Nemesio Diez | W 4-1 |
| Sun. 27 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET1:00 (+1) GMT2:00 1:00 1:00 AM 3:00 KSA12:00 AM AET6:30 (+1) IST8:30 PM VEN5:00 (+1) UAE9:00 AM SST9:00 8:00 6:00 PM MST7:00 PM CST8:00 PM EST20:00 ET20:00 22:00 BRT21:00 6:00 PM CT | Santos | Estadio Azteca | L 1-2 |
| March 2022 |
| Date | Time | Opponent | Venue | Result |
| Wed. 2 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET1:00 (+1) GMT2:00 1:00 1:00 AM 3:00 KSA12:00 AM AET6:30 (+1) IST8:30 PM VEN5:00 (+1) UAE9:00 AM SST9:00 8:00 6:00 PM MST7:00 PM CST8:00 PM EST20:00 ET20:00 22:00 BRT21:00 6:00 PM CT | Tigres | Estadio Universitario de Nuevo Leon | D 2-2 |
| Sat. 5 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST22:00 ET22:00 0:00 BRT23:00 8:00 PM CT | Puebla | Estadio Azteca | L 1-3 |
| Sat. 12 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET1:00 (+1) GMT2:00 1:00 1:00 AM 3:00 KSA12:00 AM AET6:30 (+1) IST8:30 PM VEN5:00 (+1) UAE9:00 AM SST9:00 8:00 6:00 PM MST7:00 PM CST8:00 PM EST20:00 ET20:00 22:00 BRT21:00 6:00 PM CT | Pumas | Estadio Azteca | W 2-1 |
| Sat. 19 | 8:00 PM PT9:00 PM MT10:00 PM CT11:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST23:00 ET22:00 0:00 BRT23:00 9:00 PM CT | Pachuca | Estadio Hidalgo | L 0-1 |
| April 2022 |
| Date | Time | Opponent | Venue | Result |
| Sat. 2 | 4:00 PM PT5:00 PM MT6:00 PM CT7:00 PM ET23:00 GMT0:00 23:00 11:00 PM 1:00 KSA10:00 AM AET4:30 (+1) IST6:30 PM VEN3:00 (+1) UAE7:00 AM SST7:00 6:00 4:00 PM MST5:00 PM CST6:00 PM EST19:00 ET18:00 20:00 BRT19:00 5:00 PM CT | Atlas | Estadio Azteca | W 1-0 |
| Fri. 8 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET2:00 (+1) GMT3:00 2:00 2:00 AM 4:00 KSA13:00 AM AET7:30 (+1) IST9:30 PM VEN6:00 (+1) UAE10:00 AM SST10:00 9:00 7:00 PM MST8:00 PM CST9:00 PM EST22:00 ET21:00 23:00 BRT22:00 9:00 PM CT | Mazatlan | Estadio de Mazatlan | D 1-1 |
| Sat. 16 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET2:00 (+1) GMT3:00 2:00 2:00 AM 4:00 KSA13:00 AM AET7:30 (+1) IST9:30 PM VEN6:00 (+1) UAE10:00 AM SST10:00 9:00 7:00 PM MST8:00 PM CST9:00 PM EST22:00 ET21:00 23:00 BRT22:00 9:00 PM CT | Guadalajara | Estadio Azteca | L 0-1 |
| Thu. 21 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET2:00 (+1) GMT3:00 2:00 2:00 AM 4:00 KSA13:00 AM AET7:30 (+1) IST9:30 PM VEN6:00 (+1) UAE10:00 AM SST10:00 9:00 7:00 PM MST8:00 PM CST9:00 PM EST22:00 ET21:00 23:00 BRT22:00 9:00 PM CT | Querétaro | Estadio La Corregidora | W 1-0 |
| Sun. 24 | 3:00 PM PT4:00 PM MT5:00 PM CT6:00 PM ET22:00 GMT23:00 22:00 10:00 PM 0:00 KSA9:00 AM AET3:30 (+1) IST5:30 PM VEN2:00 (+1) UAE6:00 AM SST6:00 5:00 3:00 PM MST4:00 PM CST5:00 PM EST18:00 ET17:00 19:00 BRT18:00 5:00 PM CT | Atlético de San Luis | Estadio Azteca | L 0-1 |
| Sat. 30 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET2:00 (+1) GMT3:00 2:00 2:00 AM 4:00 KSA13:00 AM AET7:30 (+1) IST9:30 PM VEN6:00 (+1) UAE10:00 AM SST10:00 9:00 7:00 PM MST8:00 PM CST9:00 PM EST22:00 ET21:00 23:00 BRT22:00 9:00 PM CT | América | Estadio Azteca | D 0-0 |
| May 2022 |
| Date | Time | Opponent | Venue | Result |
| Sat. 7 | 3:45 PM PT4:45 PM MT5:45 PM CT6:45 PM ET22:45 GMT23:45 22:45 10:45 PM 0:45 KSA9:45 AM AET4:15 (+1) IST6:15 PM VEN2:45 (+1) UAE6:45 AM SST6:45 5:45 3:45 PM MST4:45 PM CST5:45 PM EST18:45 ET17:45 19:45 BRT18:45 5:45 PM CT | Necaxa | Estadio Azteca | D 1-1 |
| Thu. 12 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET0:00 (+1) GMT1:00 0:00 12:00 AM 2:00 KSA11:00 AM AET5:30 (+1) IST7:30 PM VEN4:00 (+1) UAE8:00 AM SST8:00 7:00 5:00 PM MST6:00 PM CST7:00 PM EST20:00 ET19:00 21:00 BRT20:00 7:00 PM CT | Tigres | Estadio Azteca | L 0-1 |
| Sun. 15 | 6:05 PM PT7:05 PM MT8:05 PM CT9:05 PM ET1:05 (+1) GMT2:05 1:05 1:05 AM 3:05 KSA12:05 AM AET6:35 (+1) IST8:35 PM VEN5:05 (+1) UAE9:05 AM SST9:05 8:05 6:05 PM MST7:05 PM CST8:05 PM EST21:05 ET20:05 22:05 BRT21:05 8:05 PM CT | Tigres | Estadio Universitario de Nuevo Leon | W 1-0 |
@STATS_Football
