| January 2022 |
| Date | Time | Opponent | Venue | Result |
| Thu. 6 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST22:00 ET22:00 23:00 BRT23:00 8:00 PM CT | Pachuca | Estadio Alfonso Lastras Ramirez | L 0-2 |
| Sat. 15 | 3:00 PM PT4:00 PM MT5:00 PM CT6:00 PM ET23:00 GMT0:00 23:00 11:00 PM 1:00 KSA10:00 AM AET4:30 (+1) IST6:30 PM VEN3:00 (+1) UAE7:00 AM SST7:00 6:00 4:00 PM MST5:00 PM CST6:00 PM EST18:00 ET18:00 19:00 BRT19:00 4:00 PM CT | Atlas | Estadio Jalisco | L 0-1 |
| Thu. 20 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST22:00 ET22:00 23:00 BRT23:00 8:00 PM CT | FC Juárez | Estadio Alfonso Lastras Ramirez | L 0-1 |
| February 2022 |
| Date | Time | Opponent | Venue | Result |
| Sat. 5 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET1:00 (+1) GMT2:00 1:00 1:00 AM 3:00 KSA12:00 AM AET6:30 (+1) IST8:30 PM VEN5:00 (+1) UAE9:00 AM SST9:00 8:00 6:00 PM MST7:00 PM CST8:00 PM EST20:00 ET20:00 21:00 BRT21:00 6:00 PM CT | América | Estadio Azteca | W 3-2 |
| Sat. 12 | 3:00 PM PT4:00 PM MT5:00 PM CT6:00 PM ET23:00 GMT0:00 23:00 11:00 PM 1:00 KSA10:00 AM AET4:30 (+1) IST6:30 PM VEN3:00 (+1) UAE7:00 AM SST7:00 6:00 4:00 PM MST5:00 PM CST6:00 PM EST18:00 ET18:00 19:00 BRT19:00 4:00 PM CT | Toluca | Estadio Alfonso Lastras Ramirez | L 0-1 |
| Sat. 19 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET1:00 (+1) GMT2:00 1:00 1:00 AM 3:00 KSA12:00 AM AET6:30 (+1) IST8:30 PM VEN5:00 (+1) UAE9:00 AM SST9:00 8:00 6:00 PM MST7:00 PM CST8:00 PM EST20:00 ET20:00 21:00 BRT21:00 6:00 PM CT | Tigres | Estadio Universitario de Nuevo Leon | L 1-2 |
| Sat. 26 | 3:06 PM PT4:06 PM MT5:06 PM CT6:06 PM ET23:06 GMT0:06 23:06 11:06 PM 1:06 KSA10:06 AM AET4:36 (+1) IST6:36 PM VEN3:06 (+1) UAE7:06 AM SST7:06 6:06 4:06 PM MST5:06 PM CST6:06 PM EST18:06 ET18:06 20:06 BRT19:06 4:06 PM CT | Monterrey | Estadio BBVA | W 2-0 |
| March 2022 |
| Date | Time | Opponent | Venue | Result |
| Wed. 2 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET3:00 (+1) GMT4:00 3:00 3:00 AM 5:00 KSA14:00 AM AET8:30 (+1) IST10:30 PM VEN7:00 (+1) UAE11:00 AM SST11:00 10:00 8:00 PM MST9:00 PM CST10:00 PM EST22:00 ET22:00 0:00 BRT23:00 8:00 PM CT | Guadalajara | Estadio Alfonso Lastras Ramirez | D 2-2 |
| Sun. 6 | 7:06 PM PT8:06 PM MT9:06 PM CT10:06 PM ET3:06 (+1) GMT4:06 3:06 3:06 AM 5:06 KSA14:06 AM AET8:36 (+1) IST10:36 PM VEN7:06 (+1) UAE11:06 AM SST11:06 10:06 8:06 PM MST9:06 PM CST10:06 PM EST22:06 ET22:06 0:06 BRT23:06 8:06 PM CT | Tijuana | Estadio Caliente | Postponed |
| Sun. 13 | 4:00 PM PT5:00 PM MT6:00 PM CT7:00 PM ET23:00 GMT0:00 23:00 11:00 PM 1:00 KSA10:00 AM AET4:30 (+1) IST6:30 PM VEN3:00 (+1) UAE7:00 AM SST7:00 6:00 4:00 PM MST5:00 PM CST6:00 PM EST19:00 ET18:00 20:00 BRT19:00 5:00 PM CT | Puebla | Estadio Alfonso Lastras Ramirez | W 2-1 |
| Thu. 17 | 8:05 PM PT9:05 PM MT10:05 PM CT11:05 PM ET3:05 (+1) GMT4:05 3:05 3:05 AM 5:05 KSA14:05 AM AET8:35 (+1) IST10:35 PM VEN7:05 (+1) UAE11:05 AM SST11:05 10:05 8:05 PM MST9:05 PM CST10:05 PM EST23:05 ET22:05 0:05 BRT23:05 9:05 PM CT | Querétaro | Estadio Generalisimo Jose Maria Morelos y Pavon | L 1-2 |
| April 2022 |
| Date | Time | Opponent | Venue | Result |
| Fri. 1 | 7:00 PM PT8:00 PM MT9:00 PM CT10:00 PM ET2:00 (+1) GMT3:00 2:00 2:00 AM 4:00 KSA13:00 AM AET7:30 (+1) IST9:30 PM VEN6:00 (+1) UAE10:00 AM SST10:00 9:00 7:00 PM MST8:00 PM CST9:00 PM EST22:00 ET21:00 23:00 BRT22:00 8:00 PM CT | Mazatlan | Estadio Alfonso Lastras Ramirez | W 1-0 |
| Wed. 6 | 7:06 PM PT8:06 PM MT9:06 PM CT10:06 PM ET2:06 (+1) GMT3:06 2:06 2:06 AM 4:06 KSA13:06 AM AET7:36 (+1) IST9:36 PM VEN6:06 (+1) UAE10:06 AM SST10:06 9:06 7:06 PM MST8:06 PM CST9:06 PM EST22:06 ET21:06 23:06 BRT22:06 9:06 PM CT | Tijuana | Estadio Caliente | D 1-1 |
| Sat. 9 | 3:00 PM PT4:00 PM MT5:00 PM CT6:00 PM ET22:00 GMT23:00 22:00 10:00 PM 0:00 KSA9:00 AM AET3:30 (+1) IST5:30 PM VEN2:00 (+1) UAE6:00 AM SST6:00 5:00 3:00 PM MST4:00 PM CST5:00 PM EST18:00 ET17:00 19:00 BRT18:00 5:00 PM CT | León | Estadio Alfonso Lastras Ramirez | W 2-0 |
| Fri. 15 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET0:00 (+1) GMT1:00 0:00 12:00 AM 2:00 KSA11:00 AM AET5:30 (+1) IST7:30 PM VEN4:00 (+1) UAE8:00 AM SST8:00 7:00 5:00 PM MST6:00 PM CST7:00 PM EST20:00 ET19:00 21:00 BRT20:00 7:00 PM CT | Necaxa | Estadio Victoria de Aguascalientes | L 2-4 |
| Wed. 20 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET0:00 (+1) GMT1:00 0:00 12:00 AM 2:00 KSA11:00 AM AET5:30 (+1) IST7:30 PM VEN4:00 (+1) UAE8:00 AM SST8:00 7:00 5:00 PM MST6:00 PM CST7:00 PM EST20:00 ET19:00 21:00 BRT20:00 7:00 PM CT | Pumas | Estadio Alfonso Lastras Ramirez | W 2-0 |
| Sun. 24 | 3:00 PM PT4:00 PM MT5:00 PM CT6:00 PM ET22:00 GMT23:00 22:00 10:00 PM 0:00 KSA9:00 AM AET3:30 (+1) IST5:30 PM VEN2:00 (+1) UAE6:00 AM SST6:00 5:00 3:00 PM MST4:00 PM CST5:00 PM EST18:00 ET17:00 19:00 BRT18:00 5:00 PM CT | Cruz Azul | Estadio Azteca | W 1-0 |
| May 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 1 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Santos | Estadio Alfonso Lastras Ramirez | L 1-3 |
| Sat. 7 | 6:06 PM PT7:06 PM MT8:06 PM CT9:06 PM ET1:06 (+1) GMT2:06 1:06 1:06 AM 3:06 KSA12:06 AM AET6:36 (+1) IST8:36 PM VEN5:06 (+1) UAE9:06 AM SST9:06 8:06 6:06 PM MST7:06 PM CST8:06 PM EST21:06 ET20:06 22:06 BRT21:06 8:06 PM CT | Monterrey | Estadio BBVA | D 2-2 |
| Wed. 11 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET0:00 (+1) GMT1:00 0:00 12:00 AM 2:00 KSA11:00 AM AET5:30 (+1) IST7:30 PM VEN4:00 (+1) UAE8:00 AM SST8:00 7:00 5:00 PM MST6:00 PM CST7:00 PM EST20:00 ET19:00 21:00 BRT20:00 7:00 PM CT | Pachuca | Estadio Alfonso Lastras Ramirez | D 2-2 |
| Sat. 14 | 6:05 PM PT7:05 PM MT8:05 PM CT9:05 PM ET1:05 (+1) GMT2:05 1:05 1:05 AM 3:05 KSA12:05 AM AET6:35 (+1) IST8:35 PM VEN5:05 (+1) UAE9:05 AM SST9:05 8:05 6:05 PM MST7:05 PM CST8:05 PM EST21:05 ET20:05 22:05 BRT21:05 8:05 PM CT | Pachuca | Estadio Hidalgo | - |
@STATS_Football
