| August 2021 |
| Date | Time | Opponent | Venue | Result |
| Fri. 6 | 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET19:00 GMT20:00 19:00 7:00 PM 21:00 KSA6:00 AM AET0:30 (+1) IST2:30 PM VEN23:00 UAE3:00 AM SST3:00 2:00 12:00 PM MST1:00 PM CST2:00 PM EST15:00 ET14:00 16:00 BRT15:00 2:00 PM CT | Monaco | Stade Louis II | D 1-1 |
| Sun. 15 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Metz | Stade de la Beaujoire - Louis Fonteneau | W 2-0 |
| Sun. 22 | 8:00 AM PT9:00 AM MT10:00 AM CT11:00 AM ET15:00 GMT16:00 15:00 3:00 PM 17:00 KSA2:00 AM AET20:30 IST10:30 AM VEN19:00 UAE11:00 PM SST23:00 22:00 8:00 AM MST9:00 AM CST10:00 AM EST11:00 ET10:00 12:00 BRT11:00 10:00 AM CT | Rennes | Roazhon Park | L 0-1 |
| Fri. 27 | 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET19:00 GMT20:00 19:00 7:00 PM 21:00 KSA6:00 AM AET0:30 (+1) IST2:30 PM VEN23:00 UAE3:00 AM SST3:00 2:00 12:00 PM MST1:00 PM CST2:00 PM EST15:00 ET14:00 16:00 BRT15:00 2:00 PM CT | Olympique Lyonnais | Stade de la Beaujoire - Louis Fonteneau | L 0-1 |
| September 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 12 | 8:00 AM PT9:00 AM MT10:00 AM CT11:00 AM ET15:00 GMT16:00 15:00 3:00 PM 17:00 KSA2:00 AM AET20:30 IST10:30 AM VEN19:00 UAE11:00 PM SST23:00 22:00 8:00 AM MST9:00 AM CST10:00 AM EST11:00 ET10:00 12:00 BRT11:00 10:00 AM CT | Nice | Stade de la Beaujoire - Louis Fonteneau | L 0-2 |
| Sun. 19 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Angers SCO | Stade Raymond-Kopa | W 4-1 |
| Wed. 22 | 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET17:00 GMT18:00 17:00 5:00 PM 19:00 KSA4:00 AM AET22:30 IST12:30 PM VEN21:00 UAE1:00 AM SST1:00 0:00 10:00 AM MST11:00 AM CST12:00 PM EST13:00 ET12:00 14:00 BRT13:00 12:00 PM CT | Brest | Stade de la Beaujoire - Louis Fonteneau | W 3-1 |
| Sun. 26 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Reims | Stade Auguste-Delaune II | L 1-3 |
| October 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 3 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Troyes | Stade de la Beaujoire - Louis Fonteneau | W 2-0 |
| Sun. 17 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Bordeaux | Stade Matmut-Atlantique | D 1-1 |
| Sat. 23 | 8:00 AM PT9:00 AM MT10:00 AM CT11:00 AM ET15:00 GMT16:00 15:00 3:00 PM 17:00 KSA2:00 AM AET20:30 IST10:30 AM VEN19:00 UAE11:00 PM SST23:00 22:00 8:00 AM MST9:00 AM CST10:00 AM EST11:00 ET10:00 12:00 BRT11:00 10:00 AM CT | Clermont | Stade de la Beaujoire - Louis Fonteneau | |
| Sun. 31 | 7:00 AM PT8:00 AM MT9:00 AM CT10:00 AM ET14:00 GMT15:00 14:00 2:00 PM 16:00 KSA1:00 AM AET19:30 IST9:30 AM VEN18:00 UAE10:00 PM SST22:00 21:00 7:00 AM MST8:00 AM CST9:00 AM EST10:00 ET9:00 11:00 BRT10:00 9:00 AM CT | Montpellier | Stade de la Mosson | |
| November 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 7 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET14:00 GMT15:00 14:00 2:00 PM 16:00 KSA1:00 AM AET19:30 IST9:30 AM VEN18:00 UAE10:00 PM SST22:00 21:00 7:00 AM MST8:00 AM CST9:00 AM EST9:00 ET9:00 11:00 BRT10:00 7:00 AM CT | Strasbourg | Stade de la Beaujoire - Louis Fonteneau | |
| Sat. 20 | 8:00 AM PT9:00 AM MT10:00 AM CT11:00 AM ET16:00 GMT17:00 16:00 4:00 PM 18:00 KSA3:00 AM AET21:30 IST11:30 AM VEN20:00 UAE12:00 AM SST0:00 23:00 9:00 AM MST10:00 AM CST11:00 AM EST11:00 ET11:00 12:00 BRT12:00 9:00 AM CT | PSG | Parc des Princes | |
| Sun. 28 | TBA | Lille | Stade Pierre-Mauroy | |
| December 2021 |
| Date | Time | Opponent | Venue | Result |
| Wed. 1 | TBA | Olympique Marseille | Stade de la Beaujoire - Louis Fonteneau | |
| Sun. 5 | TBA | Lorient | Stade Yves Allainmat - Le Moustoir | |
| Sun. 12 | TBA | Lens | Stade de la Beaujoire - Louis Fonteneau | |
| Wed. 22 | TBA | Saint-Etienne | Stade Geoffroy-Guichard | |
| January 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 9 | TBA | Monaco | Stade de la Beaujoire - Louis Fonteneau | |
| Sun. 16 | TBA | Nice | Allianz Riviera | |
| Sun. 23 | TBA | Lorient | Stade de la Beaujoire - Louis Fonteneau | |
| February 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 6 | TBA | Strasbourg | Stade de la Meinau | |
| Sun. 13 | TBA | Reims | Stade de la Beaujoire - Louis Fonteneau | |
| Sun. 20 | TBA | PSG | Stade de la Beaujoire - Louis Fonteneau | |
| Sun. 27 | TBA | Metz | Stade Saint-Symphorien | |
| March 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 6 | TBA | Montpellier | Stade de la Beaujoire - Louis Fonteneau | |
| Sun. 13 | TBA | Troyes | Stade de l'Aube | |
| Sun. 20 | TBA | Lille | Stade de la Beaujoire - Louis Fonteneau | |
| April 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 3 | TBA | Clermont | Stade Gabriel Montpied | |
| Sun. 10 | TBA | Brest | Stade Francis-Le Ble | |
| Sun. 17 | TBA | Angers SCO | Stade de la Beaujoire - Louis Fonteneau | |
| Wed. 20 | TBA | Olympique Marseille | Orange Velodrome | |
| Sun. 24 | TBA | Bordeaux | Stade de la Beaujoire - Louis Fonteneau | |
| May 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 1 | TBA | Lens | Stade Bollaert-Delelis | |
| Sun. 8 | TBA | Rennes | Stade de la Beaujoire - Louis Fonteneau | |
| Sat. 14 | TBA | Olympique Lyonnais | Groupama Stadium | |
| Sat. 21 | TBA | Saint-Etienne | Stade de la Beaujoire - Louis Fonteneau | |
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