| Friday, 1 October 2021 |
| Time/Result | Home | Away | Venue |
| 4-1 |
NAC Breda |
Excelsior | Rat Verlegh Stadion |
| 0-1 |
Den Bosch |
Telstar | Stadion De Vliert |
| 2-0 |
Roda JC |
Eindhoven | Parkstad Limburg Stadion |
| 3-2 |
Volendam |
Almere City | Kras Stadion |
| 3-1 |
Helmond Sport |
Ajax II | SolarUnie Stadion |
| 2-6 |
MVV |
ADO Den Haag | De Geusselt |
| 0-3 |
TOP Oss |
De Graafschap | Frans Heesen Stadion |
| 2-1 |
PSV II |
VVV | Sportcomplex De Herdgang |
| 0-1 |
Utrecht II |
Emmen | Sportpark Zoudenbalch Veld 4 |
| 2-1 |
AZ II |
Dordrecht | AFAS Trainingscomplex |
| Saturday, 9 October 2021 |
| Time/Result | Home | Away | Venue |
| 2-0 |
VVV |
MVV | Covebo Stadion - De Koel - |
| 0-1 |
Emmen |
Excelsior | De Oude Meerdijk |
| 2-1 |
Eindhoven |
TOP Oss | Jan Louwers Stadion |
| Sunday, 10 October 2021 |
| Time/Result | Home | Away | Venue |
| 3-2 |
ADO Den Haag |
Den Bosch | Cars Jeans Stadion |
| 0-1 |
Dordrecht |
Helmond Sport | Riwal Hoogwerkers Stadion |
| 1-2 |
Almere City |
De Graafschap | Yanmar Stadion |
| Friday, 15 October 2021 |
| Time/Result | Home | Away | Venue |
| 1-0 |
NAC Breda |
AZ II | Rat Verlegh Stadion |
| 1-0 |
Den Bosch |
Almere City | Stadion De Vliert |
| 2-2 |
Roda JC |
PSV II | Parkstad Limburg Stadion |
| 0-0 |
De Graafschap |
Eindhoven | Stadion De Vijverberg |
| 3-0 |
Excelsior |
VVV | Van Donge & De Roo Stadion |
| 0-0 |
Helmond Sport |
ADO Den Haag | SolarUnie Stadion |
| 2-1 |
MVV |
Dordrecht | De Geusselt |
| 1-5 |
Telstar |
Volendam | BUKO Stadion |
| 1-2 |
TOP Oss |
Emmen | Frans Heesen Stadion |
| 3-1 |
Ajax II |
Utrecht II | Sportpark De Toekomst |
| Monday, 18 October 2021 |
| Time/Result | Home | Away | Venue |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Volendam |
NAC Breda | Kras Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
PSV II |
Telstar | Sportcomplex De Herdgang |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Utrecht II |
Roda JC | Sportpark Zoudenbalch Veld 4 |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
AZ II |
Ajax II | AFAS Trainingscomplex |
| Friday, 22 October 2021 |
| Time/Result | Home | Away | Venue |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
NAC Breda |
MVV | Rat Verlegh Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
ADO Den Haag |
Excelsior | Cars Jeans Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
VVV |
De Graafschap | Covebo Stadion - De Koel - |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Dordrecht |
Den Bosch | Riwal Hoogwerkers Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Eindhoven |
Ajax II | Jan Louwers Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Almere City |
PSV II | Yanmar Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Telstar |
Helmond Sport | BUKO Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Utrecht II |
TOP Oss | Sportpark Zoudenbalch Veld 4 |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
AZ II |
Volendam | AFAS Trainingscomplex |
| Saturday, 23 October 2021 |
| Time/Result | Home | Away | Venue |
| 7:30 AM PT8:30 AM MT9:30 AM CT10:30 AM ET14:30 GMT15:30 14:30 2:30 PM 16:30 KSA1:30 AM AET20:00 IST10:00 AM VEN18:30 UAE10:30 PM SST22:30 21:30 7:30 AM MST8:30 AM CST9:30 AM EST10:30 ET9:30 11:30 BRT10:30 9:30 AM CT |
Roda JC |
Emmen | Parkstad Limburg Stadion |
| Friday, 29 October 2021 |
| Time/Result | Home | Away | Venue |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Den Bosch |
Utrecht II | Stadion De Vliert |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
De Graafschap |
ADO Den Haag | Stadion De Vijverberg |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Volendam |
Dordrecht | Kras Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Emmen |
VVV | De Oude Meerdijk |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
MVV |
Roda JC | De Geusselt |
| Saturday, 30 October 2021 |
| Time/Result | Home | Away | Venue |
| 7:30 AM PT8:30 AM MT9:30 AM CT10:30 AM ET14:30 GMT15:30 14:30 2:30 PM 16:30 KSA1:30 AM AET20:00 IST10:00 AM VEN18:30 UAE10:30 PM SST22:30 21:30 7:30 AM MST8:30 AM CST9:30 AM EST10:30 ET9:30 11:30 BRT10:30 9:30 AM CT |
Excelsior |
Eindhoven | Van Donge & De Roo Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
TOP Oss |
NAC Breda | Frans Heesen Stadion |
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