| Friday, 3 September 2021 |
| Time/Result | Home | Away | Venue |
| 0-5 |
Den Bosch |
Excelsior | Stadion De Vliert |
| 1-0 |
Helmond Sport |
Emmen | SolarUnie Stadion |
| Saturday, 4 September 2021 |
| Time/Result | Home | Away | Venue |
| 3-0 |
Almere City |
TOP Oss | Yanmar Stadion |
| Sunday, 5 September 2021 |
| Time/Result | Home | Away | Venue |
| 3-0 |
MVV |
Telstar | De Geusselt |
| 4-2 |
ADO Den Haag |
Eindhoven | Cars Jeans Stadion |
| 0-1 |
Dordrecht |
VVV | Riwal Hoogwerkers Stadion |
| Friday, 10 September 2021 |
| Time/Result | Home | Away | Venue |
| 0-0 |
Roda JC |
NAC Breda | Parkstad Limburg Stadion |
| 0-3 |
De Graafschap |
Volendam | Stadion De Vijverberg |
| 3-1 |
Excelsior |
Dordrecht | Van Donge & De Roo Stadion |
| 2-1 |
VVV |
Den Bosch | Covebo Stadion - De Koel - |
| 7-1 |
Emmen |
MVV | De Oude Meerdijk |
| 1-1 |
Telstar |
Almere City | BUKO Stadion |
| 3-3 |
TOP Oss |
ADO Den Haag | Frans Heesen Stadion |
| 3-1 |
PSV II |
Ajax II | Sportcomplex De Herdgang |
| 0-1 |
AZ II |
Utrecht II | AFAS Trainingscomplex |
| Monday, 13 September 2021 |
| Time/Result | Home | Away | Venue |
| 2-2 |
Volendam |
Roda JC | Kras Stadion |
| 3-2 |
Eindhoven |
Helmond Sport | Jan Louwers Stadion |
| 6-3 |
Ajax II |
NAC Breda | Sportpark De Toekomst |
| 2-1 |
Utrecht II |
PSV II | Sportpark Zoudenbalch Veld 4 |
| 2-1 |
AZ II |
De Graafschap | AFAS Trainingscomplex |
| Friday, 17 September 2021 |
| Time/Result | Home | Away | Venue |
| 1-2 |
NAC Breda |
Emmen | Rat Verlegh Stadion |
| 2-1 |
Den Bosch |
AZ II | Stadion De Vliert |
| 2-0 |
Roda JC |
TOP Oss | Parkstad Limburg Stadion |
| 3-1 |
De Graafschap |
Excelsior | Stadion De Vijverberg |
| 2-1 |
Volendam |
VVV | Kras Stadion |
| 0-1 |
Dordrecht |
Telstar | Riwal Hoogwerkers Stadion |
| 0-3 |
Helmond Sport |
Utrecht II | SolarUnie Stadion |
| 1-0 |
MVV |
Eindhoven | De Geusselt |
| 2-4 |
Almere City |
Ajax II | Yanmar Stadion |
| Monday, 20 September 2021 |
| Time/Result | Home | Away | Venue |
| 0-1 |
PSV II |
ADO Den Haag | Sportcomplex De Herdgang |
| Friday, 24 September 2021 |
| Time/Result | Home | Away | Venue |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
De Graafschap |
Utrecht II | Stadion De Vijverberg |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Excelsior |
PSV II | Van Donge & De Roo Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
ADO Den Haag |
Roda JC | Cars Jeans Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
VVV |
Helmond Sport | Covebo Stadion - De Koel - |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Eindhoven |
NAC Breda | Jan Louwers Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Emmen |
Den Bosch | De Oude Meerdijk |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Almere City |
Dordrecht | Yanmar Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Telstar |
AZ II | BUKO Stadion |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
TOP Oss |
Volendam | Frans Heesen Stadion |
| Monday, 27 September 2021 |
| Time/Result | Home | Away | Venue |
| 11:00 AM PT12:00 PM MT1:00 PM CT2:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST14:00 ET13:00 15:00 BRT14:00 1:00 PM CT |
Ajax II |
MVV | Sportpark De Toekomst |
@STATS_Football
