| Monday, 1 February 2021 |
| Time/Result | Home | Away | Venue |
| 3-2 |
AZ II |
Eindhoven | AFAS Trainingscomplex |
| 4-0 |
NAC Breda |
Almere City | Rat Verlegh Stadion |
| Tuesday, 2 February 2021 |
| Time/Result | Home | Away | Venue |
| 1-3 |
Go Ahead Eagles |
Volendam | De Adelaarshorst |
| Friday, 5 February 2021 |
| Time/Result | Home | Away | Venue |
| 0-2 |
Eindhoven |
Go Ahead Eagles | Jan Louwers Stadion |
| 6-0 |
TOP Oss |
AZ II | Frans Heesen Stadion |
| 5-1 |
Roda JC |
PSV II | Parkstad Limburg Stadion |
| 0-2 |
Volendam |
Excelsior | Kras Stadion |
| Saturday, 6 February 2021 |
| Time/Result | Home | Away | Venue |
| 2-3 |
Den Bosch |
De Graafschap | Stadion De Vliert |
| 2-1 |
MVV |
NEC | De Geusselt |
| Sunday, 7 February 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
Helmond Sport |
Almere City | SolarUnie Stadion |
| Postponed |
Telstar |
NAC Breda | BUKO Stadion |
| Monday, 8 February 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
Utrecht II |
Dordrecht | Sportcomplex Zoudenbalch 1e veld |
| Postponed |
Ajax II |
Cambuur | Sportpark De Toekomst |
| Friday, 12 February 2021 |
| Time/Result | Home | Away | Venue |
| 2-1 |
NAC Breda |
Eindhoven | Rat Verlegh Stadion |
| 3-2 |
AZ II |
Utrecht II | AFAS Trainingscomplex |
| Postponed |
PSV II |
Helmond Sport | Sportcomplex De Herdgang |
| Postponed |
Almere City |
Volendam | Yanmar Stadion |
| Saturday, 13 February 2021 |
| Time/Result | Home | Away | Venue |
| 1-0 |
Go Ahead Eagles |
Telstar | Erve Asito |
| 1-0 |
De Graafschap |
MVV | Stadion De Vijverberg |
| Sunday, 14 February 2021 |
| Time/Result | Home | Away | Venue |
| Postponed |
NEC |
Den Bosch | Goffertstadion |
| Monday, 15 February 2021 |
| Time/Result | Home | Away | Venue |
| 1-2 |
Ajax II |
Dordrecht | Sportpark De Toekomst |
| 1-3 |
Excelsior |
Roda JC | Van Donge & De Roo Stadion |
| Tuesday, 16 February 2021 |
| Time/Result | Home | Away | Venue |
| 2-1 |
Helmond Sport |
Almere City | SolarUnie Stadion |
| 3-0 |
Cambuur |
TOP Oss | Cambuurstadion |
| 1-2 |
Telstar |
NAC Breda | BUKO Stadion |
| Friday, 19 February 2021 |
| Time/Result | Home | Away | Venue |
| 1-1 |
Ajax II |
Cambuur | Sportpark De Toekomst |
| 2-3 |
Dordrecht |
NAC Breda | Riwal Hoogwerkers Stadion |
| 1-0 |
PSV II |
Den Bosch | Sportcomplex De Herdgang |
| 1-2 |
Helmond Sport |
Roda JC | SolarUnie Stadion |
| 1-1 |
Telstar |
Eindhoven | BUKO Stadion |
| Saturday, 20 February 2021 |
| Time/Result | Home | Away | Venue |
| 2-4 |
TOP Oss |
Almere City | Frans Heesen Stadion |
| 1-0 |
MVV |
Excelsior | De Geusselt |
| Sunday, 21 February 2021 |
| Time/Result | Home | Away | Venue |
| 1-2 |
NEC |
De Graafschap | Goffertstadion |
| Monday, 22 February 2021 |
| Time/Result | Home | Away | Venue |
| 0-3 |
AZ II |
Go Ahead Eagles | AFAS Trainingscomplex |
| 1-3 |
Utrecht II |
Cambuur | Sportcomplex Zoudenbalch 1e veld |
| Tuesday, 23 February 2021 |
| Time/Result | Home | Away | Venue |
| 3-2 |
Volendam |
Ajax II | Kras Stadion |
| 2-2 |
PSV II |
Helmond Sport | Sportcomplex De Herdgang |
| Friday, 26 February 2021 |
| Time/Result | Home | Away | Venue |
| 9:45 AM PT10:45 AM MT11:45 AM CT12:45 PM ET17:45 GMT18:45 17:45 5:45 PM 19:45 KSA4:45 AM AET23:15 IST1:15 PM VEN21:45 UAE1:45 AM SST1:45 0:45 10:45 AM MST11:45 AM CST12:45 PM EST12:45 ET12:45 14:45 BRT13:45 10:45 AM CT |
Go Ahead Eagles |
PSV II | De Adelaarshorst |
| 9:45 AM PT10:45 AM MT11:45 AM CT12:45 PM ET17:45 GMT18:45 17:45 5:45 PM 19:45 KSA4:45 AM AET23:15 IST1:15 PM VEN21:45 UAE1:45 AM SST1:45 0:45 10:45 AM MST11:45 AM CST12:45 PM EST12:45 ET12:45 14:45 BRT13:45 10:45 AM CT |
MVV |
Telstar | De Geusselt |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 17:00 BRT16:00 1:00 PM CT |
Den Bosch |
Utrecht II | Stadion De Vliert |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 17:00 BRT16:00 1:00 PM CT |
Roda JC |
NEC | Parkstad Limburg Stadion |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 17:00 BRT16:00 1:00 PM CT |
De Graafschap |
AZ II | Stadion De Vijverberg |
| Saturday, 27 February 2021 |
| Time/Result | Home | Away | Venue |
| 5:00 AM PT6:00 AM MT7:00 AM CT8:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST8:00 ET8:00 10:00 BRT9:00 6:00 AM CT |
Eindhoven |
Volendam | Jan Louwers Stadion |
| 7:30 AM PT8:30 AM MT9:30 AM CT10:30 AM ET15:30 GMT16:30 15:30 3:30 PM 17:30 KSA2:30 AM AET21:00 IST11:00 AM VEN19:30 UAE11:30 PM SST23:30 22:30 8:30 AM MST9:30 AM CST10:30 AM EST10:30 ET10:30 12:30 BRT11:30 8:30 AM CT |
Dordrecht |
Helmond Sport | Riwal Hoogwerkers Stadion |
| Sunday, 28 February 2021 |
| Time/Result | Home | Away | Venue |
| 3:15 AM PT4:15 AM MT5:15 AM CT6:15 AM ET11:15 GMT12:15 11:15 11:15 AM 13:15 KSA10:15 PM AET16:45 IST6:45 AM VEN15:15 UAE7:15 PM SST19:15 18:15 4:15 AM MST5:15 AM CST6:15 AM EST6:15 ET6:15 8:15 BRT7:15 4:15 AM CT |
Almere City |
Cambuur | Yanmar Stadion |
@STATS_Football
