| Saturday, 2 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 2-1 |
17 | Villarreal |
Levante | Estadio de la Cerámica |
| 1-1 |
17 | Real Betis |
Sevilla | Benito Villamarín |
| 0-1 |
17 | Getafe |
Real Valladolid | Coliseum Alfonso Perez |
| 2-0 |
17 | Real Madrid |
Celta de Vigo | Alfredo Di Stéfano |
| Sunday, 3 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 1-0 |
17 | Athletic Club |
Elche | San Mamés |
| 1-2 |
17 | Alavés |
Atlético Madrid | Estadio de Mendizorroza |
| 1-1 |
17 | Real Sociedad |
Osasuna | Reale Arena |
| 2-0 |
17 | Eibar |
Granada | Estadio Municipal de Ipurua |
| 0-1 |
17 | Huesca |
Barcelona | Estadio El Alcoraz |
| Monday, 4 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 1-1 |
17 | València |
Cádiz | Estadio de Mestalla |
| Wednesday, 6 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 2-3 |
2 | Athletic Club |
Barcelona | San Mamés |
| Friday, 8 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 0-4 |
18 | Celta de Vigo |
Villarreal | Abanca-Balaidos |
| Saturday, 9 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 3-2 |
18 | Sevilla |
Real Sociedad | Ramon Sanchez Pizjuan |
| Postponed |
18 | Atlético Madrid |
Athletic Club | Estadio Wanda Metropolitano |
| 0-4 |
18 | Granada |
Barcelona | Los Cármenes |
| 0-0 |
18 | Osasuna |
Real Madrid | Estadio El Sadar |
| Sunday, 10 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 2-1 |
18 | Levante |
Eibar | Ciutat de València |
| 3-1 |
18 | Cádiz |
Alavés | Ramón de Carranza |
| Postponed |
18 | Elche |
Getafe | Estadio Manuel Martinez Valero |
| 0-1 |
18 | Real Valladolid |
València | José Zorrilla |
| Monday, 11 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 1-3 |
18 | Elche |
Getafe | Estadio Manuel Martinez Valero |
| 0-2 |
18 | Huesca |
Real Betis | Estadio El Alcoraz |
| Tuesday, 12 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 2-0 |
4 | Granada |
Osasuna | Los Cármenes |
| 2-0 |
1 | Atlético Madrid |
Sevilla | Estadio Wanda Metropolitano |
| Tuesday, 19 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST13:00 ET13:00 14:00 BRT14:00 11:00 AM CT |
19 | Real Valladolid |
Elche | José Zorrilla |
| 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST13:00 ET13:00 14:00 BRT14:00 11:00 AM CT |
19 | Cádiz |
Levante | Ramón de Carranza |
| 12:30 PM PT1:30 PM MT2:30 PM CT3:30 PM ET20:30 GMT21:30 20:30 8:30 PM 22:30 KSA7:30 AM AET2:00 (+1) IST4:00 PM VEN0:30 (+1) UAE4:30 AM SST4:30 3:30 1:30 PM MST2:30 PM CST3:30 PM EST15:30 ET15:30 16:30 BRT16:30 1:30 PM CT |
19 | Alavés |
Sevilla | Estadio de Mendizorroza |
| Wednesday, 20 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST13:00 ET13:00 14:00 BRT14:00 11:00 AM CT |
19 | Getafe |
Huesca | Coliseum Alfonso Perez |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
19 | Real Betis |
Celta de Vigo | Benito Villamarín |
| 12:30 PM PT1:30 PM MT2:30 PM CT3:30 PM ET20:30 GMT21:30 20:30 8:30 PM 22:30 KSA7:30 AM AET2:00 (+1) IST4:00 PM VEN0:30 (+1) UAE4:30 AM SST4:30 3:30 1:30 PM MST2:30 PM CST3:30 PM EST15:30 ET15:30 16:30 BRT16:30 1:30 PM CT |
19 | Villarreal |
Granada | Estadio de la Cerámica |
| Thursday, 21 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 10:00 AM PT11:00 AM MT12:00 PM CT1:00 PM ET18:00 GMT19:00 18:00 6:00 PM 20:00 KSA5:00 AM AET23:30 IST1:30 PM VEN22:00 UAE2:00 AM SST2:00 1:00 11:00 AM MST12:00 PM CST1:00 PM EST13:00 ET13:00 14:00 BRT14:00 11:00 AM CT |
19 | València |
Osasuna | Estadio de Mestalla |
| 12:30 PM PT1:30 PM MT2:30 PM CT3:30 PM ET20:30 GMT21:30 20:30 8:30 PM 22:30 KSA7:30 AM AET2:00 (+1) IST4:00 PM VEN0:30 (+1) UAE4:30 AM SST4:30 3:30 1:30 PM MST2:30 PM CST3:30 PM EST15:30 ET15:30 16:30 BRT16:30 1:30 PM CT |
19 | Eibar |
Atlético Madrid | Estadio Municipal de Ipurua |
| Friday, 22 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
20 | Levante |
Real Valladolid | Ciutat de València |
| Saturday, 23 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 5:00 AM PT6:00 AM MT7:00 AM CT8:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST8:00 ET8:00 9:00 BRT9:00 6:00 AM CT |
20 | Huesca |
Villarreal | Estadio El Alcoraz |
| 7:15 AM PT8:15 AM MT9:15 AM CT10:15 AM ET15:15 GMT16:15 15:15 3:15 PM 17:15 KSA2:15 AM AET20:45 IST10:45 AM VEN19:15 UAE11:15 PM SST23:15 22:15 8:15 AM MST9:15 AM CST10:15 AM EST10:15 ET10:15 11:15 BRT11:15 8:15 AM CT |
20 | Sevilla |
Cádiz | Ramon Sanchez Pizjuan |
| 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET17:30 GMT18:30 17:30 5:30 PM 19:30 KSA4:30 AM AET23:00 IST1:00 PM VEN21:30 UAE1:30 AM SST1:30 0:30 10:30 AM MST11:30 AM CST12:30 PM EST12:30 ET12:30 13:30 BRT13:30 10:30 AM CT |
20 | Real Sociedad |
Real Betis | Reale Arena |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
20 | Alavés |
Real Madrid | Estadio de Mendizorroza |
| Sunday, 24 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 5:00 AM PT6:00 AM MT7:00 AM CT8:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST8:00 ET8:00 9:00 BRT9:00 6:00 AM CT |
20 | Osasuna |
Granada | Estadio El Sadar |
| 7:15 AM PT8:15 AM MT9:15 AM CT10:15 AM ET15:15 GMT16:15 15:15 3:15 PM 17:15 KSA2:15 AM AET20:45 IST10:45 AM VEN19:15 UAE11:15 PM SST23:15 22:15 8:15 AM MST9:15 AM CST10:15 AM EST10:15 ET10:15 11:15 BRT11:15 8:15 AM CT |
20 | Elche |
Barcelona | Estadio Manuel Martinez Valero |
| 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET17:30 GMT18:30 17:30 5:30 PM 19:30 KSA4:30 AM AET23:00 IST1:00 PM VEN21:30 UAE1:30 AM SST1:30 0:30 10:30 AM MST11:30 AM CST12:30 PM EST12:30 ET12:30 13:30 BRT13:30 10:30 AM CT |
20 | Celta de Vigo |
Eibar | Abanca-Balaidos |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
20 | Atlético Madrid |
València | Estadio Wanda Metropolitano |
| Monday, 25 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| 12:00 PM PT1:00 PM MT2:00 PM CT3:00 PM ET20:00 GMT21:00 20:00 8:00 PM 22:00 KSA7:00 AM AET1:30 (+1) IST3:30 PM VEN0:00 (+1) UAE4:00 AM SST4:00 3:00 1:00 PM MST2:00 PM CST3:00 PM EST15:00 ET15:00 16:00 BRT16:00 1:00 PM CT |
20 | Athletic Club |
Getafe | San Mamés |
| Sunday, 31 January 2021 |
| Time/Result | Matchday | Home | Away | Venue |
| TBA |
21 | Barcelona |
Athletic Club | Camp Nou |
| TBA |
21 | Real Madrid |
Levante | Alfredo Di Stéfano |
| TBA |
21 | València |
Elche | Estadio de Mestalla |
| TBA |
21 | Real Valladolid |
Huesca | José Zorrilla |
| TBA |
21 | Villarreal |
Real Sociedad | Estadio de la Cerámica |
| TBA |
21 | Real Betis |
Osasuna | Benito Villamarín |
| TBA |
21 | Getafe |
Alavés | Coliseum Alfonso Perez |
| TBA |
21 | Cádiz |
Atlético Madrid | Ramón de Carranza |
| TBA |
21 | Eibar |
Sevilla | Estadio Municipal de Ipurua |
| TBA |
21 | Granada |
Celta de Vigo | Los Cármenes |
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