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| 4:00 PM PT5:00 PM MT6:00 PM CT7:00 PM ET23:00 GMT7:00 4:00 PM MST6:00 PM EST3:00 UAE (+1)19:00 ET20:00 BRT, April 14, 2022 KeyBank Center, Buffalo, New York Attendance: 11,565 |
StL  |  | Buf  |
| Scoring Summary | ||||
| 1st Period | ||||
| 12:20 | Rasmus Asplund Assists: Henri Jokiharju | Sabres 1-0 | ||
| 19:36 | David Perron (Power Play) Assists: Torey Krug, Vladimir Tarasenko | Tied 1-1 | ||
| 2nd Period | ||||
| 0:17 | Brandon Saad (Power Play) Assists: Robert Thomas, Vladimir Tarasenko | Blues 2-1 | ||
| 4:20 | Alex Tuch Assists: Owen Power, Tage Thompson | Tied 2-2 | ||
| 7:18 | Vladimir Tarasenko Assists: Pavel Buchnevich, Robert Thomas | Blues 3-2 | ||
| 12:45 | Vladimir Tarasenko Assists: Torey Krug, Robert Thomas | Blues 4-2 | ||
| 3rd Period | ||||
| 6:18 | Pavel Buchnevich Assists: Colton Parayko, Robert Thomas | Blues 5-2 | ||
| 17:32 | Vladimir Tarasenko (ENG)
Assists: Pavel Buchnevich, Robert Thomas | Blues 6-2 | ||
| Penalties | ||||
| 1st Period | ||||
| 5:19 | Rasmus Dahlin | Hooking | 2:00 | |
| 14:50 | Brandon Saad | Hi Stick | 2:00 | |
| 18:08 | Cody Eakin | Hooking | 2:00 | |
| 19:05 | Owen Power | Cross Check | 2:00 | |
| 2nd Period | ||||
| No Penalties | ||||
| 3rd Period | ||||
| 14:24 | Ivan Barbashev | Slashing | 2:00 | |
| Shots on Goal | ||||
| Team | 1 | 2 | 3 | Tot |
| St. Louis Blues | 9 | 9 | 10 | 28 |
| Buffalo Sabres | 7 | 13 | 17 | 37 |
| Goaltenders | ||||
| Team | Goaltender | Shots | Saves | Record |
| St. Louis Blues | Jordan Binnington | 37 | 35 | 15-13 |
| Buffalo Sabres | Craig Anderson | 27 | 22 | 15-12 |
| Power Play Conversions: StL - 2 of 3, Buf - 0 of 2 |
Officials: Beau Halkidis, Garrett Rank
Linesmen: Scott Cherrey, Caleb Apperson
Linesmen: Scott Cherrey, Caleb Apperson
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