| August 2021 |
| Date | Time | Opponent | Venue | Result |
| Sat. 21 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST12:30 ET11:30 13:30 BRT12:30 11:30 AM CT | Sassuolo | Stadio Marc'Antonio Bentegodi | L 2-3 |
| Fri. 27 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Inter Milan | Stadio Marc'Antonio Bentegodi | L 1-3 |
| September 2021 |
| Date | Time | Opponent | Venue | Result |
| Mon. 13 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Bologna | Stadio Renato Dall'Ara | L 0-1 |
| Sun. 19 | 9:00 AM PT10:00 AM MT11:00 AM CT12:00 PM ET16:00 GMT17:00 16:00 4:00 PM 18:00 KSA3:00 AM AET21:30 IST11:30 AM VEN20:00 UAE12:00 AM SST0:00 23:00 9:00 AM MST10:00 AM CST11:00 AM EST12:00 ET11:00 13:00 BRT12:00 11:00 AM CT | Roma | Stadio Marc'Antonio Bentegodi | W 3-2 |
| Wed. 22 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST12:30 ET11:30 13:30 BRT12:30 11:30 AM CT | Salernitana | Stadio Arechi | D 2-2 |
| Sat. 25 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Genoa | Stadio Comunale Luigi Ferraris | D 3-3 |
| October 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 3 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Spezia | Stadio Marc'Antonio Bentegodi | W 4-0 |
| Sat. 16 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Milan | Stadio Giuseppe Meazza | L 2-3 |
| Sun. 24 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET13:00 GMT14:00 13:00 1:00 PM 15:00 KSA12:00 AM AET18:30 IST8:30 AM VEN17:00 UAE9:00 PM SST21:00 20:00 6:00 AM MST7:00 AM CST8:00 AM EST9:00 ET8:00 10:00 BRT9:00 8:00 AM CT | Lazio | Stadio Marc'Antonio Bentegodi | |
| Wed. 27 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST12:30 ET11:30 13:30 BRT12:30 11:30 AM CT | Udinese | Dacia Arena | |
| Sat. 30 | 9:00 AM PT10:00 AM MT11:00 AM CT12:00 PM ET16:00 GMT17:00 16:00 4:00 PM 18:00 KSA3:00 AM AET21:30 IST11:30 AM VEN20:00 UAE12:00 AM SST0:00 23:00 9:00 AM MST10:00 AM CST11:00 AM EST12:00 ET11:00 13:00 BRT12:00 11:00 AM CT | Juventus | Stadio Marc'Antonio Bentegodi | |
| November 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 7 | 9:00 AM PT10:00 AM MT11:00 AM CT12:00 PM ET17:00 GMT18:00 17:00 5:00 PM 19:00 KSA4:00 AM AET22:30 IST12:30 PM VEN21:00 UAE1:00 AM SST1:00 0:00 10:00 AM MST11:00 AM CST12:00 PM EST12:00 ET12:00 14:00 BRT13:00 10:00 AM CT | Napoli | Stadio Diego Armando Maradona | |
| Mon. 22 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET17:30 GMT18:30 17:30 5:30 PM 19:30 KSA4:30 AM AET23:00 IST1:00 PM VEN21:30 UAE1:30 AM SST1:30 0:30 10:30 AM MST11:30 AM CST12:30 PM EST12:30 ET12:30 13:30 BRT13:30 10:30 AM CT | Empoli | Stadio Marc'Antonio Bentegodi | |
| Sat. 27 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET14:00 GMT15:00 14:00 2:00 PM 16:00 KSA1:00 AM AET19:30 IST9:30 AM VEN18:00 UAE10:00 PM SST22:00 21:00 7:00 AM MST8:00 AM CST9:00 AM EST9:00 ET9:00 10:00 BRT10:00 7:00 AM CT | Sampdoria | Stadio Comunale Luigi Ferraris | |
| Tue. 30 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET19:45 GMT20:45 19:45 7:45 PM 21:45 KSA6:45 AM AET1:15 (+1) IST3:15 PM VEN23:45 UAE3:45 AM SST3:45 2:45 12:45 PM MST1:45 PM CST2:45 PM EST14:45 ET14:45 15:45 BRT15:45 12:45 PM CT | Cagliari | Stadio Marc'Antonio Bentegodi | |
| December 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 5 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET14:00 GMT15:00 14:00 2:00 PM 16:00 KSA1:00 AM AET19:30 IST9:30 AM VEN18:00 UAE10:00 PM SST22:00 21:00 7:00 AM MST8:00 AM CST9:00 AM EST9:00 ET9:00 10:00 BRT10:00 7:00 AM CT | Venezia | Stadio Pierluigi Penzo | |
| Sun. 12 | 6:00 AM PT7:00 AM MT8:00 AM CT9:00 AM ET14:00 GMT15:00 14:00 2:00 PM 16:00 KSA1:00 AM AET19:30 IST9:30 AM VEN18:00 UAE10:00 PM SST22:00 21:00 7:00 AM MST8:00 AM CST9:00 AM EST9:00 ET9:00 10:00 BRT10:00 7:00 AM CT | Atalanta | Stadio Marc'Antonio Bentegodi | |
| Sun. 19 | 9:00 AM PT10:00 AM MT11:00 AM CT12:00 PM ET17:00 GMT18:00 17:00 5:00 PM 19:00 KSA4:00 AM AET22:30 IST12:30 PM VEN21:00 UAE1:00 AM SST1:00 0:00 10:00 AM MST11:00 AM CST12:00 PM EST12:00 ET12:00 13:00 BRT13:00 10:00 AM CT | Torino | Stadio Olimpico Grande Torino | |
| Wed. 22 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET17:30 GMT18:30 17:30 5:30 PM 19:30 KSA4:30 AM AET23:00 IST1:00 PM VEN21:30 UAE1:30 AM SST1:30 0:30 10:30 AM MST11:30 AM CST12:30 PM EST12:30 ET12:30 13:30 BRT13:30 10:30 AM CT | Fiorentina | Stadio Marc'Antonio Bentegodi | |
| January 2022 |
| Date | Time | Opponent | Venue | Result |
| Thu. 6 | TBA | Spezia | Stadio Alberto Picco | |
| Sun. 9 | TBA | Salernitana | Stadio Marc'Antonio Bentegodi | |
| Sun. 16 | TBA | Sassuolo | Stadio Città del Tricolore | |
| Sun. 23 | TBA | Bologna | Stadio Marc'Antonio Bentegodi | |
| February 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 6 | TBA | Juventus | Allianz Stadium | |
| Sun. 13 | TBA | Udinese | Stadio Marc'Antonio Bentegodi | |
| Sun. 20 | TBA | Roma | Stadio Olimpico | |
| Sun. 27 | TBA | Venezia | Stadio Marc'Antonio Bentegodi | |
| March 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 6 | TBA | Fiorentina | Stadio Artemio Franchi | |
| Sun. 13 | TBA | Napoli | Stadio Marc'Antonio Bentegodi | |
| Sun. 20 | TBA | Empoli | Stadio Carlo Castellani | |
| April 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 3 | TBA | Genoa | Stadio Marc'Antonio Bentegodi | |
| Sun. 10 | TBA | Inter Milan | Stadio Giuseppe Meazza | |
| Sat. 16 | TBA | Atalanta | Gewiss Stadium | |
| Sun. 24 | TBA | Sampdoria | Stadio Marc'Antonio Bentegodi | |
| May 2022 |
| Date | Time | Opponent | Venue | Result |
| Sun. 1 | TBA | Cagliari | Unipol Domus | |
| Sun. 8 | TBA | Milan | Stadio Marc'Antonio Bentegodi | |
| Sun. 15 | TBA | Torino | Stadio Marc'Antonio Bentegodi | |
| Sun. 22 | TBA | Lazio | Stadio Olimpico | |
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