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| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Aleksandar Kovacevic | Win | 6-3, 6-2, 7-6 (7-1) |
| Second Round | Marton Fucsovics | Win | 7-6 (7-2), 6-0, 6-3 |
| Third Round | Alejandro Davidovich Fokina | Win | 7-6 (7-4), 7-6 (7-5), 6-2 |
| Fourth Round | Juan Pablo Varillas | Win | 6-3, 6-2, 6-2 |
| Quarterfinals | Karen Khachanov | Win | 4-6, 7-6 (7-0), 6-2, 6-4 |
| Semifinals | Carlos Alcaraz |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Tomas Martin Etcheverry | Win | 7-6 (7-5), 6-2 |
| Third Round | Grigor Dimitrov | Win | 6-3, 4-6, 6-1 |
| Fourth Round | Cameron Norrie | Win | 6-3, 6-4 |
| Quarterfinals | Holger Rune | Loss | 2-6, 6-4, 2-6 |
| Banja Luka Open | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Luca Van Assche | Win | 6-7 (4-7), 6-3, 6-2 |
| Quarterfinals | Dusan Lajovic | Loss | 4-6, 6-7 (6-8) |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 9 - Apr. 16 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ivan Gakhov | Win | 7-6 (7-5), 6-2 |
| Third Round | Lorenzo Musetti | Loss | 6-4, 5-7, 4-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 27 - Mar. 4 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Tomas Machac | Win | 6-3, 3-6, 7-6 (7-1) |
| Second Round | Tallon Griekspoor | Win | 6-2, 6-3 |
| Quarterfinals | Hubert Hurkacz | Win | 6-3, 7-5 |
| Semifinals | Daniil Medvedev | Loss | 4-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Roberto Carballes Baena | Win | |
| Second Round | Enzo Couacaud | Win | |
| Third Round | Grigor Dimitrov | Win | |
| Fourth Round | Alex De Minaur | Win | |
| Quarterfinals | Andrey Rublev | Win | |
| Semifinals | Tommy Paul | Win | |
| Final | Stefanos Tsitsipas | Win |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Constant Lestienne | Win | |
| Second Round | Quentin Halys | Win | |
| Quarterfinals | Denis Shapovalov | Win | |
| Semifinals | Daniil Medvedev | Win | |
| Final | Sebastian Korda | Win |
