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| Hengqin Life WTA Elite Trophy | ||
| Surface: Hard | Date: Oct. 22 - Oct. 27 | Seed: 7 |
| Round | Opponent | W / L | Result |
| Round Robin | Sofia Kenin | Loss | 4-6, 4-6 6-2, 2-6, 5-7 |
| Round Robin | Karolina Muchova | Loss | 4-6, 4-6 6-2, 2-6, 5-7 |
| China Open | ||
| Surface: Hard | Date: Sep. 28 - Oct. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ajla Tomljanovic | Win | 6-3, 3-6, 6-4 |
| Third Round | Naomi Osaka | Loss | 4-6, 0-6 |
| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 22 - Sep. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kateryna Kozlova | Win | 4-6, 6-3, 6-3 |
| Second Round | Monica Puig | Win | 2-6, 7-6 (7-5), 6-3 |
| Third Round | Qiang Wang | Win | 6-2, 6-1 |
| Quarterfinals | Elina Svitolina | Win | 6-1, 6-3 |
| Semifinals | Petra Kvitova | Win | 7-5, 7-5 |
| Final | Aryna Sabalenka | Loss | 3-6, 6-3, 1-6 |
| Toray Pan Pacific Open | ||
| Surface: Decoturf | Date: Sep. 16 - Sep. 22 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nicole Gibbs | Loss | 4-6, 3-6 |
| Zhengzhou Open | ||
| Surface: Hard | Date: Sep. 9 - Sep. 15 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Angelique Kerber | Win | 5-7, 6-4, 7-6 (8-6) |
| Second Round | Saisai Zheng | Loss | 5-7, 3-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Garbine Muguruza | Win | 2-6, 6-1, 6-3 |
| Second Round | Jelena Ostapenko | Loss | 4-6, 3-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Maria Sharapova | Loss | 3-6, 6-7 (4-7) |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Maria Sakkari | Win | 4-6, 6-2, 7-6 (9-7) |
| Second Round | Karolina Pliskova | Loss | 4-6, 7-6 (7-4), 2-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Win | 3-6, 6-3, 7-5 |
| Second Round | Ivana Jorovic | Win | 6-2, 6-7 (3-7), 9-7 |
| Third Round | Belinda Bencic | Win | 4-6, 6-4, 6-4 |
| Fourth Round | Ashleigh Barty | Win | 3-6, 6-2, 6-3 |
| Quarterfinals | Serena Williams | Loss | 4-6, 6-4, 3-6 |
| Mallorca Open | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Paula Badosa Gibert | Loss | 7-6 (7-2), 5-7, 5-7 |
| Libema Open | ||
| Surface: Grass | Date: Jun. 10 - Jun. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Karolina Muchova | Win | 6-7 (4-7), 6-3, 6-2 |
| Second Round | Polona Hercog | Win | 6-4, 7-6 (7-5) |
| Quarterfinals | Ekaterina Alexandrova | Win | 7-5, 6-3 |
| Semifinals | Veronika Kudermetova | Win | 6-4, 3-6, 7-6 (7-5) |
| Final | Kiki Bertens | Win | 0-6, 7-6 (7-3), 7-5 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Andrea Petkovic | Loss | 6-2, 3-6, 5-7 |
| Nurnberger Versicherungscup | ||
| Surface: Clay | Date: May 19 - May 25 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Nina Stojanovic | Loss | 6-7 (6-8), 6-2, 2-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Johanna Konta | Loss | 4-6, 1-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Johanna Konta | Loss | 4-6, 1-6 |
| Abierto GNP Seguros | ||
| Surface: Hard | Date: Apr. 1 - Apr. 7 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Sachia Vickery | Loss | 6-7 (6-8), 1-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kaia Kanepi | Win | 6-2, 6-2 |
| Second Round | Su-Wei Hsieh | Loss | 2-6, 5-7 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alison Van Uytvanck | Loss | 6-7 (1-7), 4-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 17 - Feb. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Julia Goerges | Win | 6-4, 7-5 |
| Second Round | Alize Cornet | Win | 6-2, 6-3 |
| Third Round | Karolina Pliskova | Loss | 6-7 (3-7), 6-7 (5-7) |
| Qatar Total Open | ||
| Surface: Hard | Date: Feb. 11 - Feb. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Polona Hercog | Win | 6-4, 6-3 |
| Second Round | Julia Goerges | Loss | 1-6, 7-6 (7-5), 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kiki Bertens | Loss | 3-6, 3-6 |
| Shenzhen Gemdale Open | ||
| Surface: Hard | Date: Dec. 31 - Jan. 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Qiang Wang | Win | 6-3, 6-3 |
| Second Round | Evgeniya Rodina | Win | 4-6, 6-2, 6-3 |
| Quarterfinals | Sorana Cirstea | Win | 7-5, 6-1 |
| Semifinals | Vera Zvonareva | Win | 6-0, 1-0 Retired |
| Final | Aryna Sabalenka | Loss | 6-4, 6-7 (2-7), 3-6 |
