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| US Open | ||
| Surface: Hard | Date: Aug. 29 - Sep. 11 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Naomi Osaka | Win | 7-6 (7-5), 6-3 |
| Second Round | Cristina Bucsa | Win | 6-2, 7-5 |
| Third Round | Alize Cornet | Win | 6-4, 7-6 (11-9) |
| Fourth Round | Aryna Sabalenka | Loss | 6-3, 3-6, 2-6 |
| Ladies Championship Lausanne | ||
| Surface: Clay | Date: Jul. 11 - Jul. 17 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Simona Waltert | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 27 - Jul. 10 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Marie Bouzkova | Loss |
| Roland Garros | ||
| Surface: Red Clay | Date: May 22 - Jun. 5 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Viktoriya Tomova | Win | |
| Second Round | Shelby Rogers | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 8 - May 15 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Simona Halep | Win | |
| Third Round | Amanda Anisimova | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 28 - May 8 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Monica Puig | Win | |
| Second Round | Bianca Andreescu | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 3 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Anna Bondar | Win | |
| Third Round | Vera Zvonareva | Win | |
| Fourth Round | Ons Jabeur | Win | |
| Quarterfinals | Naomi Osaka | Loss |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 14 - Feb. 19 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Marketa Vondrousova | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 17 - Jan. 30 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Caroline Dolehide | Win | |
| Second Round | Ana Konjuh | Win | |
| Third Round | Clara Tauson | Win | |
| Fourth Round | Elise Mertens | Win | |
| Quarterfinals | Alize Cornet | Win | |
| Semifinals | Iga Swiatek | Win | |
| Final | Ashleigh Barty | Loss |
